Wendy M Mars Selected Research

1,4- bis(2- (3,5- dichloropyridyloxy))benzene

1/2022	Lymphocyte-Specific Protein-1 Suppresses Xenobiotic-Induced Constitutive Androstane Receptor and Subsequent Yes-Associated Protein-Activated Hepatocyte Proliferation.
1/2021	Yes-Associated Protein Is Crucial for Constitutive Androstane Receptor-Driven Hepatocyte Proliferation But Not for Induction of Drug Metabolism Genes in Mice.
1/2019	TCPOBOP-Induced Hepatomegaly and Hepatocyte Proliferation are Attenuated by Combined Disruption of MET and EGFR Signaling.
8/2011	Hepatocyte proliferation and hepatomegaly induced by phenobarbital and 1,4-bis [2-(3,5-dichloropyridyloxy)] benzene is suppressed in hepatocyte-targeted glypican 3 transgenic mice.
2/2011	Excessive hepatomegaly of mice with hepatocyte-targeted elimination of integrin linked kinase following treatment with 1,4-bis [2-(3,5-dichaloropyridyloxy)] benzene.

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Wendy M Mars Research Topics

Disease

7	Fibrosis (Cirrhosis) 11/2019 - 11/2002
5	Hepatomegaly 01/2021 - 12/2008
4	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 01/2003
4	Inflammation (Inflammations) 01/2019 - 04/2007
3	Infections 01/2021 - 08/2009
2	Hyperplasia 01/2019 - 02/2011
2	Liver Failure 10/2018 - 05/2018
2	Acute-Phase Reaction 01/2014 - 11/2010
1	Hypertrophy 01/2022
1	Sepsis (Septicemia) 01/2021
1	Non-alcoholic Fatty Liver Disease 11/2019
1	Fatty Liver 11/2019
1	Obesity 01/2019
1	Liver Diseases (Liver Disease) 05/2018
1	End Stage Liver Disease 05/2018
1	Ascites 11/2016
1	Liver Neoplasms (Liver Cancer) 01/2013
1	Acute Liver Failure (Fulminant Hepatic Failure) 11/2011
1	Body Weight (Weight, Body) 11/2011
1	Liver Cirrhosis (Hepatic Cirrhosis) 09/2011
1	Seizures (Absence Seizure) 01/2010
1	Kidney Diseases (Kidney Disease) 05/2008
1	Chronic Renal Insufficiency 05/2008
1	Necrosis 04/2007
1	Hepatitis 04/2007
1	Hemorrhagic Shock 08/2005
1	Fibrolamellar hepatocellular carcinoma 01/2003

Drug/Important Bio-Agent (IBA)

5	Benzene (Benzole)IBA 01/2022 - 02/2011
5	1,4- bis(2- (3,5- dichloropyridyloxy))benzeneIBA 01/2022 - 02/2011
4	Constitutive Androstane ReceptorIBA 01/2022 - 02/2011
4	CytokinesIBA 01/2019 - 12/2007
4	Tissue Plasminogen Activator (Alteplase)FDA Link 10/2014 - 11/2002
4	integrin-linked kinaseIBA 11/2011 - 04/2007
3	Transcription Factors (Transcription Factor)IBA 01/2022 - 05/2018
3	ErbB Receptors (EGF Receptor)IBA 11/2019 - 10/2018
3	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 01/2010 - 04/2002
2	MitogensIBA 01/2022 - 08/2011
2	Pharmaceutical PreparationsIBA 01/2022 - 01/2021
2	XenobioticsIBA 01/2022 - 08/2011
2	ezrinIBA 01/2020 - 05/2018
2	Glucose (Dextrose)FDA LinkGeneric 11/2019 - 01/2019
2	Proto-Oncogene Proteins c-metIBA 01/2019 - 01/2003
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2019 - 01/2003
2	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 01/2019 - 01/2003
2	Plasminogen Activator Inhibitor 1IBA 01/2019 - 08/2005
2	GlypicansIBA 01/2018 - 08/2011
2	Peptide Hydrolases (Proteases)FDA Link 10/2014 - 01/2003
2	Interleukin-6 (Interleukin 6)IBA 01/2014 - 11/2010
2	Fibrinolysin FDA Link 09/2011 - 01/2003
1	LigandsIBA 01/2022
1	F-actin-binding proteinsIBA 01/2022
1	Heme Oxygenase-1IBA 01/2021
1	Heme (Haem)IBA 01/2021
1	NSC668394IBA 01/2020
1	SterolsIBA 11/2019
1	Hepatocyte Nuclear Factor 4IBA 11/2019
1	CarbohydratesIBA 11/2019
1	Carrier Proteins (Binding Protein)IBA 11/2019
1	PPAR gammaIBA 11/2019
1	ElementsIBA 11/2019
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 11/2019
1	Canertinib (CI 1033)IBA 11/2019
1	Plasminogen InactivatorsIBA 01/2019
1	tyrosine receptor (receptor, tyrosine)IBA 01/2019
1	Phosphotransferases (Kinase)IBA 01/2019
1	Antifibrinolytic Agents (Antifibrinolytics)IBA 01/2019
1	radixinIBA 05/2018
1	BilirubinIBA 05/2018
1	Factor VII (Proconvertin)IBA 05/2018
1	Ornithine Carbamoyltransferase (Ornithine Transcarbamylase)IBA 05/2018
1	moesinIBA 05/2018
1	Cadherins (E-Cadherin)IBA 05/2018
1	Myosin Light Chains (Myosin Essential Light Chain)IBA 05/2018
1	CCAAT-Enhancer-Binding ProteinsIBA 05/2018
1	Low Density Lipoprotein Receptor-Related Protein-1 (LDL-Receptor Related Protein)IBA 05/2018
1	Hepatocyte Nuclear FactorsIBA 05/2018
1	Cytochrome P-450 CYP3AIBA 05/2018
1	Forkhead Transcription Factors (Forkhead Box Proteins)IBA 05/2018
1	AlbuminsIBA 05/2018
1	AmmoniaIBA 11/2016
1	Focal Adhesion Protein-Tyrosine KinasesIBA 10/2014
1	Acute-Phase Proteins (Acute-Phase Protein)IBA 01/2014
1	Biological ProductsIBA 01/2014
1	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 01/2014
1	Proteins (Proteins, Gene)FDA Link 01/2013
1	anti-Fas monoclonal antibodyIBA 11/2011
1	FibrinIBA 09/2011
1	Plasminogen Activators (Plasminogen Activator)IBA 09/2011
1	Phenobarbital (Luminal)FDA Link 08/2011
1	IntegrinsIBA 02/2011
1	LipopolysaccharidesIBA 11/2010
1	Urokinase Plasminogen Activator ReceptorsIBA 01/2010
1	TetraspaninsIBA 08/2009
1	Cre recombinaseIBA 04/2007
1	HGF activatorIBA 01/2003
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 01/2003
1	ParaffinIBA 01/2003

Therapy/Procedure

4	Hepatectomy 01/2022 - 11/2016
1	Intraperitoneal Injections 11/2011
1	Resuscitation 08/2005